A preliminary study on the safety and efficacy of the compound Unani medicine Jawarish-e-Shahi in the treatment of palpitation

Abstract

Heart palpitations are the sensations or feelings that accompany an excessively rapid, skip-beat, or fluttering heartbeat. Heart palpitations can be brought on by a variety of factors, such as anxiety, tension, fear, caffeine, nicotine, some medications, dietpills, physical activity, and fever. Herbal remedies have long been utilized widely in the therapeutic management of palpitations because available synthetic medications have substantial negative effects. The purpose of this study is to assess the safety and effectiveness of the Unani medication Jawarish-e-Shahi in patients experiencing palpitations. The information provided here is an open-level, multicentric clinical study that was carried out at the “Regional Research Institute of Unani Medicine in Aligarh”, Uttar Pradesh, from 2016 to 2019 on 74 cases of palpitation streated with Jawarish-e-Shahi. A p-value of<0.05 was proved to be significant in the statistical analysis of the presented data, which was conducted using one-way analysis of variance (ANOVA) and Dunnett's test. The study's findings, which were compared to baseline data from various follow-ups of palpitation cases treated with Jawarish-e-Shahi, demonstrated a notable improvement in a number of palpitation symptoms, including anxiety, perspiration, nausea, vomiting, and chest heaviness. A significant decline in diastolic pressure and pulse rate had also been observed. Reduction in number of pallor (pale appearance of patients) in baseline, 1^st follow-up and post-treatment had been noted. Based on the investigation, the Unani medicine is safe and non-toxic. More research on a large size of population with palpitations is suggested for further study.