Evaluation of the antimicrobial potential of Catharanthus roseus extract

Authors

  • Bhumika Arora Department of Zoology, Deshbandhu College, University of Delhi, New Delhi 110019, India
  • Shailendra Kumar Department of Zoology, Mahatma Gandhi P.G. College, DDU Gorakhpur University, Gorakhpur 273001, India
  • Kajal Narwal Medicinal Plant and Health Research Lab. Department of Zoology, Deshbandhu College, University of Delhi, New Delhi 110019, India
  • Mohd Shazad Department of Zoology, Deshbandhu College, University of Delhi, New Delhi 110019, India

DOI:

https://doi.org/10.56042/ijnpr.v15i2.12011

Keywords:

Catharanthus roseus, Escherichia coli, Growth inhibition, Leaf extract

Abstract

Catharanthus roseus L. (Apocyanaceae), also known as Madagascar periwinkle, is an evergreen herb with therapeutic qualities. The present study investigated the antibacterial activity of C. roseus leaf ethanol extract (Cr-LEE) against E. coli. The result indicated significant growth inhibitory activity of Cr-LEE on E. coli. The effects were dose-dependent. From our earlier research, GC/MS (Gas Chromatography-Mass Spectrometry) was also used to determine the significant phytoconstituents in the extract. The secondary metabolites present in the extract may individually or synergistically be responsible for the antibacterial action of C. roseus.

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Published

2024-07-31

Issue

Vol. 15 No. 2 (2024): June 2024

Section

Short Communication