Schiff base metal complexes: Synthesis, characterisation, and antibacterial properties

Authors

  • Dr. Madhukar Vainala Department of Chemistry, Kakatiya University, Warangal 506 009, India
  • Dr. Sunkari Jyothi Department of Chemistry, Kakatiya University, Warangal 506 009, India
  • Dr. Sriramoju Shamili Department of Chemistry, Vaagdevi Degree and PG College, Hanamkonda 506 001, India

DOI:

https://doi.org/10.56042/ijc.v62i7.3827

Keywords:

Schiff bases, Metal complexes, In vitro antibacterial activity

Abstract

 

Five novel metal complex derivatives from the 2N-salicylidene-5-(p-amino phenyl)-1,3,4-thiadiazole (HL) in alcoholic medium have been effectively synthesised by combining HL with the metal ions Vo(II), Co(II), Rh(III), Pd (II) and Au(III). Except for the Vo(II) and Co(II) complexes, which have square pyramidal and tetrahedral geometries, all of the complexes have a monomeric structure, with the metal centre moieties being four-coordinated. HL has been shown to be more effective in vitro against the tested bacteria and complexes 1–5 have been found to have greatest antibacterial activity relative to the standard antibiotic (Kanamycin).

Published

2023-07-20