Clinical role of sodium calcium phosphosilicate gel preparations in the prevention of enamel demineralisation in orthodontic treatment

Phosphosilicate gel adjuvant therapy for orthodontic enamel demineralisation

Authors

  • Meilin Li
  • Lili Wan
  • Fang Liu
  • Hongbo Ou The First People's Hospital of Zunyi (The Third Affiliated Hospital of Zunyi Medical University)

DOI:

https://doi.org/10.56042/ijeb.v64i06.26583

Keywords:

Sodium calcium phosphosilicate gel, Orthodontic adjuvant therapy, Enamel demineralisation prevention, Demineralisation index, Plaque control, Orthodontic enamel protection

Abstract

Enamel demineralisation is a common and complex local problem in orthodontic treatment, this study evaluated the preventive effect of sodium calcium phosphosilicate gel preparations on enamel demineralisation during orthodontic treatment to provide a basis for clinical prevention. 128 patients undergoing orthodontic treatment from The First People's Hospital of Zunyi between January 2021 and January 2023 were divided into CT and CC groups. Both groups were treated with conventional treatment, the CC group was added treatment with sodium calcium phosphosilicate gel preparation. The enamel demineralisation index (EDI), plaque index (PLI), modified bleeding index (mBI), enamel demineralisation chalky lesions and incidence of demineralisation were mainly assessed in both groups. Secondary outcomes included quality of life scores, complications and adverse reactions incidence. After treatment, the indicators of both groups were remarkably different comparing with pre-treatment (P<0.05). The EDI, PLI, mBI, enamel demineralisation chalky lesion condition, the incidence of demineralisation complication and incidence of adverse reactions in the CC group were below the CT group, and the quality of life scores were above the CT group (P<0.05). sodium calcium phosphosilicate gel preparations are effective in preventing the occurrence of enamel demineralisation during orthodontic treatment and improving the quality of life of patients.

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Published

10-06-2026

How to Cite

Clinical role of sodium calcium phosphosilicate gel preparations in the prevention of enamel demineralisation in orthodontic treatment: Phosphosilicate gel adjuvant therapy for orthodontic enamel demineralisation. (2026). Indian Journal of Experimental Biology (IJEB), 64(06), 548-559. https://doi.org/10.56042/ijeb.v64i06.26583

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