Biotransformation of steroidal compounds using Lignincola laevis

Takamitsu Utsukihara; Kazuhito Hoshiyama; Shoma Kobayashi; Masahiro Koshimura; C Akira Horiuchi

doi:10.56042/ijc.v62i4.443

Authors

Dr. Takamitsu Utsukihara Hakodate National College of Technology, Tokura-cho, Hakodate 042-8501, Japan
Dr. Kazuhito Hoshiyama Hakodate National College of Technology, Tokura-cho, Hakodate 042-8501, Japan
Dr. Shoma Kobayashi Hakodate National College of Technology, Tokura-cho, Hakodate 042-8501, Japan
Dr. Masahiro Koshimura Sasebo National College of Technology, 1-1, Okishin-cho, Sasebo City, Nagasaki 857-1171, Japan
Dr. C Akira Horiuchi Department of Chemistry, Rikkyo (St. Paul’s) University, Toshima-ku, Tokyo 171-8501, Japan

DOI:

https://doi.org/10.56042/ijc.v62i4.443

Keywords:

Biotransformation, Fungus, Steroidal compounds, Lignincola laevis

Abstract

Biotransformation of testosterone 1 and stanolone 2 has been investigated with fungus of Lignincola laevis. Biotransformaton of 1 gives 15α,17β-dihydroxyandrost-4-en-3-one 3. In the case of 2, two products, 5α-androstan-3α,17β-diol 4 and 5α-androstane-3, 17-dione 5 have been obtained.

Biotransformation of steroidal compounds using Lignincola laevis

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