Visible-Light Photocatalyzed Radical Multicomponent Reactions in Organic Synthesis: A Short Review

Abstract

This review presents recent advancements in multicomponent reactions driven by visible light photocatalysis, encompassing both metal-free and transition-metal-catalyzed strategies. It explores current challenges, promising opportunities, future directions, and real-world applications in the visible-light-mediated synthesis of organic and bioactive molecules. Practical aspects including room-temperature protocols, continuous-flow synthesis, and scalable green methodologies are discussed. By unifying these transformations under a mechanistic framework, this review provides a comprehensive and methodology-centered perspective, complementing recent heterocycle-focused reviews. Finally, this work aims to propel further innovation in photocatalytic methodologies for constructing valuable organic frameworks.