An Effect of environmental Changes on the activity of Berberine Compounds of Giloy

Atmospheric Changes on Potency of Berberine Content of Gulvel (Tinospora cordifolia, Giloy)

Abstract

Tinospora cordifolia (Thunb.) Miers, Menispermaceae, is a climbing deciduous shrub, commonly known as “Giloe” or “Guduchi” or “Amrita” with significant medicinal importance in the traditional systems of medicine of India. It is prevalent throughout the tropical regions of India, China, Bangladesh, Myanmar, and Sri Lanka. It is a well-known  medicinal  herb  that  is  utilised  in  a  number  of conventional treatments  for a wide range of illnesses. It is designated as Rasayana drug in Ayurveda and recommended as adaptogen and immunomodulator used to treat carcinoma alongwith broad variety of maladies, including diabetes, leprosy, skin disorders, diarrhoea, fever, hepatoprotective, antioxidant, anti-hyperglycemic due to presence of active constituents such as alkaloids, terpenoids, lignans, steroids etc. The safety and efficacy of herbal medicines are closely correlated with the quality of the source materials. Atmospheric variations have impact on presence of active constituents along with its quality. If collection of herbs is done properly as per standards the yield is with more potency. Plant sample used in different time and places, identification and analysis was performed. Morphological, microscopical and extractive values appear varying. The aim of this study is to check atmospheric changes on phytoconstituents and how these vary in T. cordifolia stem samples. The study revealed that berberine, reached to their highest concentration in rainy season. The results of this study suggest that the best harvesting seasons is rainy season for high yield of berberine content.