Biological activities of celery leaves, seeds and tuber parts collected from different regions

Celery's pharmacological and biological effects

Abstract

Plants, with their natural and nutritional properties, are also important sources of medicine. The study aimed to determine total phenolic, total flavonoid, total oxidant, total antioxidant, antiproliferative and antimicrobial activities of parts of the celery (Apium graveolens L.) plant. Samples of celery were gathered in Turkey and Iraq. Celery parts (leaves, tuber, and seed) were extracted with ethanol and methanol using the Soxhlet apparatus. Total phenolic (Folin-Ciocalteu reagent), total flavonoid (aluminum chloride assay), total antioxidant and total oxidant (Rel Assay kits) and antimicrobial (agar dilution method) activities of parts of the celery plant were determined. Using the MTT assay, the antiproliferative activity against the human lung cancer cell line A549 was ascertained. The study's findings indicate that, in terms of biological activity, plant samples obtained in Turkey exhibited higher levels of total oxidant activity than those collected in Iraq; additionally, the antiproliferative activity of the plants were observed to be dose dependent. Plant samples also demonstrated high levels of activity against Acinetobacter baumannii. In conclusion, it has been established that the celery plant possesses natural antibacterial, antioxidant, and anticancer properties.