Physiological Consequences of Immune Aging at Organs Level: A Mini-review

Immune Aging and organ physiology

Abstract

Aging is a discrete phenomenon and hard to understand. A coordinated and gradual loss of structure and function causes impaired responsiveness at cellular and organ levels. It makes an aged individual prone to several chronic diseases and opportunistic infections. The failed interplay among different organ systems is what orchestrates aging. Simultaneously, the involvement of more molecular participants makes it more challenging to understand and examine. This mini-review comprehensively reviewed physiological changes in immune aging and their correlation with overall aging anomalies.