Green synthesis and molinspiration analysis of novel N-substituted imide derivatives

Abstract

A series of novel N-Unsubstituted cyclic imides were synthesized using solvent free conditions using bentonite as a catalyst from anhydrides with urea. As a nitrogen source, urea gives the protocol the benefits of a smooth reaction, simple product separation, easy recovery, and bentonite recycling. The synthesised compounds were analysed using TLC, FT-IR, and 1H-NMR to determine their characteristics. The molinspiration online programme was used to predict the molecular characteristics and bioactivity of the compounds.