Schiff Base Ligand and Metal (II) complex: Synthesis, characterization and Biological Evaluation

Abstract

Mixed ligand complexes of Cu (II), Ni (II), Mg (II), Hg (II) and Fe (II) with an innovative Schiff base ligand denoted as (L1), (Z)-2-(1-hydrazineylideneethyl)-3H-benzo(F) chromen-3-one and (L2), (E)-2-(1-(2-phenylhydrazineylidene)ethyl)-3H-benzo[f]chromen-3-one, served as the principal ligand were synthesized and characterized. Assessments included elemental analyses, mass spectrometry, Fourier transform‑infrared and ultraviolet-visible spectroscopy. The Mixed ligand complex was evaluated for its antibacterial activity against four bacterial species, Two Gram-positive bacteria (Bacillus subtilis, MTCC 441 and Staphylococcus aureus, MTCC 96) and two Gram-negative bacteria (Pseudomonas aeruginosa, MTCC 1866 and Escherichia coli, MTCC 443).