EcoScale MCR sustainability to impart rapid access to pyrrolo[1,2-b]pyrazoles scaffolds assisted by recyclable HClO4‧SiO2 heterogeneous catalytic system

Authors

  • Twinkle Solanki Devi Ahilya University, Khandwa Road, Indore-452001 (M.P.)
  • Ashok Waskle Devi Ahilya University, Khandwa Road, Indore-452001 (M.P.)
  • Prakash Barfa
  • Ashok Kumar Devi Ahilya University, Khandwa Road, Indore-452001 (M.P.)
  • Pratibha Sharma Devi Ahilya University, Khandwa Road, Indore-452001 (M.P.)

DOI:

https://doi.org/10.56042/ijc.v62i11.1165

Abstract

Present work elicits an account of synthesizing a new series of pyrrolo[1,2-b]pyrazole scaffolds involving multi component reaction (MCR) strategy, assisted by silica-supported perchloric acid HClO4‧SiO2 as the heterogeneous catalyst. It embraces methyl 2-cyano-2-(phenyldiazenyl)acetate as the key precursor. The reusability of the catalyst up to five- synthetic cycles is the value-added advantage of the protocol. Moreover, feasibility of the strategy has been endorsed on the basis of EcoScale values in the sustainable limits. Structural corroboration of all the newly synthesized compounds and catalyst was ascertained by different spectroanalytical data viz., IR, 1H NMR, mass, XRD, TG/DTA, FE-SEM.

Keywords: Pyrrolo[1,2-b]pyrazole, Solvent-free, HClO4‧SiO2

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Published

2023-11-17

Issue

Vol. 62 No. 11 (2023): Indian Journal of Chemistry-(IJC)

Section

Papers

How to Cite

EcoScale MCR sustainability to impart rapid access to pyrrolo[1,2-b]pyrazoles scaffolds assisted by recyclable HClO4‧SiO2 heterogeneous catalytic system. (2023). Indian Journal of Chemistry (IJC), 62(11), 1218-1222. https://doi.org/10.56042/ijc.v62i11.1165