In vitro efficacy of phytotherapeutics for the prevention of urinary tract infections in pregnant women

Abstract

Urinary tract infections (UTIs) during pregnancy pose significant challenges due to limited treatment options to avoid potential harm to the fetus. This study investigates the in vitro efficacy of phytotherapeutics, specifically Ocimum sanctum L. (Tulsi), in preventing urinary tract infections in pregnant women. UTIs, a prevalent hospital-acquired infection and a leading cause of bacteremia in hospitalized patients, contribute to adverse pregnancy outcomes if left untreated. The research explores the potential of Tulsi, known for its diverse therapeutic benefits, including antimicrobial properties. Traditional uses as an expectorant, analgesic, anti-asthmatic, and anti-diabetic agent underscore its holistic potential in combating infections. Previous studies suggest that Ocimum sanctum L.-containing herbal medicines may mitigate the duration of sickness, clinical symptoms, and biochemical markers associated with bacterial and viral infections. This investigation aims to assess the in vitro efficacy of Ocimum sanctum leaf extract, offering valuable insights into its preventive potential against UTIs in pregnant women. The findings may contribute to the development of safe and effective phytotherapeutic interventions for managing UTIs during pregnancy.