Green synthesized copper oxide nanoparticles from Ocimum tenuiflorum fabricated in PVC for antibacterial, antioxidant, and anticancer biomedical applications

Authors

  • Johaan Ajith Prem 1Department of Oral Biology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai-600 077, Tamil Nadu, India
  • Saheb Ali Department of Periodontics, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai-600 077, Tamil Nadu, India
  • Suganya Panneer Selvam 1Department of Oral Biology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai-600 077, Tamil Nadu, India
  • Ramya Ramadoss 1Department of Oral Biology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai-600 077, Tamil Nadu, India
  • Sandhya Sundar 1Department of Oral Biology, Saveetha Dental College and Hospital, Saveetha Institute of Medical and Technical Sciences, Chennai-600 077, Tamil Nadu, India

DOI:

https://doi.org/10.56042/ijbb.v62i10.16786

Keywords:

Antibacterial, Antioxidant, Biosynthesis, Copper oxide, Nanoparticle, Ocimum tenuiflorum, Polyvinyl chloride

Abstract

Nanoparticle-coated membranes are valued for their optical, catalytic, and conductive properties, with applications in food, medicine, and electronics. This study explores the biomedical potential of green-synthesized copper oxide nanoparticles (Ot-CuO NPs) from Ocimum tenuiflorum, loaded on PVC membranes, for antibacterial, antioxidant, and anticancer activity. Copper oxide nanoparticles were synthesized via a green method, characterized using FTIR, XRD, and TEM, and assessed for bioactivity. Results revealed excellent antibacterial and antioxidant properties, enhanced by ROS production, along with anticancer potential. The eco-friendly synthesis reduces costs and environmental impact, showcasing Ot-CuO NPs-loaded PVC membranes as promising materials for biomedical applications.

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Published

2025-09-22

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Section

Papers