Gelatin/CaCl2 based cellulose nonwoven for haemostat applications

Abstract

This study investigates the controlled delivery of wound healing and clotting agents in wound dressings to enhance haemostatic efficiency. Conventional methods such as exhaustion and padding result in excessive consumption of these agents, leading to inefficiencies. To address this, electrospraying of polymer is carried out on the wound contact site. A wet-laid hemostat is developed, followed by the electrospraying of gelatin and calcium ions to improve haemostatic performance. The prepared hemostats exhibit enhanced blood clotting efficiency and phosphate buffer solution (PBS) uptake, demonstrating their potential for advanced wound dressing applications.